Biodegradable-Polymer-Blend-Based Surgical Sealant with Body-Temperature-Mediated Adhesion

Abstract

The development of practical and efficient surgical sealants has the propensity to improve operational outcomes. A biodegradable polymer blend is fabricated as a nonwoven fiber mat in situ. After direct deposition onto the tissue of interest, the material transitions from a fiber mat to a film. This transition promotes polymer–substrate interfacial interactions leading to improved adhesion and surgical sealant performance.

Publication
Advanced Materials
John L. Daristotle
John L. Daristotle
Postdoctoral Associate

I am a postdoctoral researcher in the Jaklenec Group at the Langer Lab.

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